ratio-Cyclobenzaprine Uses, Side Effects, Interactions
Acute recovery phase of myocardial infarction, and patients with arrhythmias, heart block or conduction disturbances, or congestive heart failure. Tricyclic antidepressants have been reported to produce arrhythmias, sinus tachycardia, prolongation of the conduction time leading to myocardial infarction and stroke. Talk with your doctor about other drug options that may work for you. If you have liver problems, your doctor may do a blood test to monitor how well your liver is working while you take this drug.
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Soma withdrawal is usually more severe and can include symptoms like hallucinations and seizures. For your safety and comfort, the best inpatient drug rehab center facility may include a detox program to manage withdrawal symptoms. After detox patients can transition into the actual treatment phase of the program.
Adverse Effects
Cyclobenzaprine is structurally and pharmacologically related to tricyclic antidepressants. Among the most dreaded toxicities linked with cyclical antidepressants, overdoses affect fast-acting sodium channels in the cardiac conduction system. Cyclical antidepressants block the cardiac sodium channel and cause prolongation of cardiac depolarization, which manifests as QRS widening on electrocardiograms. There is also evidence that cyclical antidepressants may decrease the seizure threshold by interfering with chloride conductance on the GABA receptor. Drug interactions of Flexeril include tricyclic antidepressants because Flexeril is chemically related to this class of drugs.
Patients taking the tablet form usually take 5mg every eight hours. However, if necessary, the prescribing doctor may increase the dose to 7.5mg or 10mg every eight hours. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Sign in to your account to save this drug interaction list. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
- In some circumstances, tizanidine might be used safely in this case.
- Call your doctor if your symptoms do not improve after 3 weeks, or if they get worse.
- If you’re taking Flexeril non-medically for a high—with or without other drugs—treatment for substance abuse can prevent you from suffering a dangerous overdose.
- Overdose symptoms may include severe drowsiness, vomiting, fast heartbeats, tremors, agitation, or hallucinations.
- Properly discard this product when it is expired or no longer needed.
In case of acute cyclobenzaprine overdose, emergency medicine physicians and triage nurses should stabilize the patient. If EKG demonstrates QRS prolongation, the clinician should initiate sodium bicarbonate therapy. In severe overdose, ventricular arrhythmias and seizures may require MICU-level of care under the supervision of a critical care physician.
MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Ask your healthcare professional how you should dispose of any medicine you do not use. The amount of medicine that you take depends on the strength of the medicine.
Gender of people who have High blood pressure when taking Flexeril*:
Many insurance companies require prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. You should not need a new prescription for this medication to be refilled.
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If you are pregnant or breastfeeding, you should also discuss using cyclobenzaprine with your healthcare provider. Both tizanidine and cyclobenzaprine can cause problems if you take them when you have certain other health issues. You should avoid what is the difference between baclofen and flexeril using cyclobenzaprine if you have a slow heart rhythm or heart rhythm problems. In some circumstances, tizanidine might be used safely in this case. Here are examples of other drugs that may interact with tizanidine and cyclobenzaprine.
The dosage is based on your medical condition and response to treatment. This medication should only be used short-term (for 3 weeks or less) unless directed by your doctor. Analysis of the data from controlled studies shows that FLEXERIL produces clinical improvement whether or not sedation occurs. In order to protect against the rare but potentially critical manifestations described above, obtain an ECG and immediately initiate cardiac monitoring. Protect the patient’s airway, establish an intravenous line and initiate gastric decontamination. Observation with cardiac monitoring and observation for signs of CNS or respiratory depression, hypotension, cardiac dysrhythmias and/or conduction blocks, and seizures is necessary.
If cyclobenzaprine is misused, taken longer than prescribed, or taken in combination with other drugs causing an interaction, withdrawal symptoms are possible. Speak with your doctor or a substance abuse counselor if you believe you’re suffering from withdrawal after discontinuing cyclobenzaprine. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.